Safe & Effective Ketamine Use: A Comprehensive Guide

This essential guide from the Ketamine Research Foundation offers clear, evidence-based recommendations for both personal and clinical ketamine use. Designed to inform individuals considering ketamine, those currently using it, and healthcare professionals, the guide provides critical insights on harm reduction, responsible usage, and ethical therapeutic practices. It highlights the risks of misuse, dependency, and addiction while outlining best practices for clinical administration. With a commitment to education, safety, and accessibility, this resource serves as a vital tool for anyone engaging with ketamine—whether for personal exploration or professional treatment.

Thank you for this work. I read it with great interest. I feel very deeply the value of the thoughtful languaging / gentle invitation for folks to contemplate how they might get into right & responsible relationship with this molecule we all love. I have many young patients who are out and about engaging this medicine in their social lives, and this tool helps me to have a more skillful conversation with them. Thank you. 

“With the rise of misuse and misunderstanding about this powerful and all-encompassing medicine, The Guidelines are the first of its kind to beautifully and thoroughly explain what ketamine is and how it can be used- from caution around the risk of abuse, to utilizing it for the purpose of healing and transformation in a therapeutic container. 

The Guidelines help explain adverse effects, and how one’s approach and intention colors the relationship and experience with the medicine. It offers the reader an invitation to look honestly within oneself at their personal relationship with the medicine, and signs for caution and dependency. It also offers a wonderful reference for practitioners on the standard of care for KAP treatment.”

-Anahita Kashefi, M.S., LMFT

“An essential and eye-opening guide for anyone considering ketamine use—whether personally or clinically. This resource is comprehensive, compassionate, and deeply insightful, offering both practical guidelines and ethical considerations. A must-read for anyone seeking safe, informed, and responsible engagement with this powerful medicine!”